Licensure follows the patient
The location that matters for telehealth is generally the patient’s, not yours. Sitting in one state and caring for a patient in Puerto Rico generally means you need authority to practice in Puerto Rico — via compact privilege or a Puerto Rico license. See telehealth: patient in another state.
Compact status is not the only consideration
Even where a multistate license reaches Puerto Rico, your employer and the Puerto Rico Board of Nurse Examiners may impose additional requirements, and some roles carry their own rules. Compact status answers one question — it is not a blanket authorization to practise remotely.
APRN telehealth is separate
The compact covers RN and LPN/LVN licenses only. If you work as an APRN, your advanced-practice authority is granted state by state and is not carried by a multistate RN license — a point that catches out a lot of remote NP roles.