What decides whether you need a new license
Two things: whether Mississippi is a compact state, and whether your own license is multistate rather than single-state. Compact privilege only exists between compact states, and only a multistate license carries it. Run your exact home/assignment pairing through the compact state checker.
Practicing in Mississippi on assignment
Working under privilege still means following Mississippi's scope of practice and nurse practice act, and you remain accountable to the Mississippi Board of Nursing while you are here. If any of the assignment is telehealth, remember licensure generally follows the patient’s location — see the Mississippi telehealth guide.
The law that governs this in Mississippi
Taking an assignment in Mississippi is practice in Mississippi, so it is Mississippi’s own nurse practice act that defines what you may do and the Mississippi Board of Nursing that applies it. That act is Miss. Code Ann. § 73-15-1 et seq. (Mississippi Nursing Practice Law).
The compact itself is separate law. Mississippi adopted it at Miss. Code Ann. § 73-15-201 (Nurse Licensure Compact), which is what allows a multistate license issued elsewhere to reach Mississippi at all — the practice act still decides what you may do once it does.
Before you sign
We are an independent licensing reference — we do not list assignments, agencies, or pay rates, and nothing here is a job offer. For the wider pre-assignment checklist (contract terms, credentialing, housing), see what to check before accepting a travel assignment. Confirm licensure with the Mississippi Board of Nursing.
Since when has a compact license worked in Mississippi?
Nurses holding another state’s multistate license have been able to practice in Mississippi since January 19, 2018. It has been a member long enough that most guidance you find will be accurate on this point.