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Telehealth nursing license requirements in Missouri

Telehealth licensing has one governing idea: you generally need authority where the patient is. Here is how that plays out for patients located in Missouri.

Do I need a Missouri license for telehealth nursing?

Generally, you need authority to practice where your patient is — so if your patient is in Missouri, Missouri licensure rules apply, even if you never leave home. Because Missouri recognizes compact privilege, an active multistate license from your compact home state generally covers telehealth to patients in Missouri. A single-state license does not. Employer policy and the Missouri State Board of Nursing’s rules may add requirements on top — confirm before you take the role.

Last reviewed 2026-06-17

Licensure follows the patient

The location that matters for telehealth is generally the patient’s, not yours. Sitting in one state and caring for a patient in Missouri generally means you need authority to practice in Missouri — via compact privilege or a Missouri license. See telehealth: patient in another state.

The law that governs this in Missouri

Caring for a patient located in Missouri is practice in Missouri, so it is Missouri’s own nurse practice act that defines what you may do and the Missouri State Board of Nursing that applies it. That act is RSMo ch. 335 (Nurses), §§ 335.011–335.096.

The compact itself is separate law. Missouri adopted it at RSMo ch. 335, Nurse Licensure Compact provisions at §§ 335.300 et seq. (incl. §§ 335.365, 335.370, 335.375), which is what allows a multistate license issued elsewhere to reach Missouri at all — the practice act still decides what you may do once it does.

Compact status is not the only consideration

Even where a multistate license reaches Missouri, your employer and the Missouri State Board of Nursing may impose additional requirements, and some roles carry their own rules. Compact status answers one question — it is not a blanket authorization to practice remotely.

APRN telehealth is separate

The compact covers RN and LPN/LVN licenses only. If you work as an APRN, your advanced-practice authority is granted state by state and is not carried by a multistate RN license — a point that catches out a lot of remote NP roles.

Since when has a compact license worked in Missouri?

Nurses holding another state’s multistate license have been able to practice in Missouri since January 19, 2018. It has been a member long enough that most guidance you find will be accurate on this point.

What usually comes next

Next-step checklist

  • Identify where your patients are located — that generally drives licensure.
  • Confirm your license reads multistate on Nursys (nursys.com) if you rely on privilege.
  • Confirm your multistate license covers Missouri, then check employer requirements.
  • If you practice as an APRN, confirm Missouri APRN authority separately with the board.

Frequently asked questions

Generally, if you hold an active multistate license from your compact home state, compact privilege reaches Missouri, which covers telehealth to patients located in Missouri. Licensure follows the patient's location. A single-state license does not carry privilege. Employer and board rules may add requirements — confirm with the Missouri State Board of Nursing.

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