Licensure follows the patient
The location that matters for telehealth is generally the patient’s, not yours. Sitting in one state and caring for a patient in Guam generally means you need authority to practice in Guam — via compact privilege or a Guam license. See telehealth: patient in another state.
Compact status is not the only consideration
Even where a multistate license reaches Guam, your employer and the Guam Board of Nurse Examiners may impose additional requirements, and some roles carry their own rules. Compact status answers one question — it is not a blanket authorization to practise remotely.
APRN telehealth is separate
The compact covers RN and LPN/LVN licenses only. If you work as an APRN, your advanced-practice authority is granted state by state and is not carried by a multistate RN license — a point that catches out a lot of remote NP roles.